Gene: [08q11/MOS] Moloney murine sarcoma viral oncogene homolog;


COM

[1] There is no agreement among different authors on the regional location of MOS. Neel-1982 and Pettenati-1989 unequivocally indicated segment 08q22; Caubet-1985 and Morris-1989 indicated segment 08q11, also unequivocally. Moreover, two reports indicated hybridization of MOS probes in both regions (q11-12 and q22), but the authors make quite opposite conclusions: Rosendorff-1987 localizes MOS to q22, and Testa-1988, to q11.
[2] The GDB/HGM catalogue, having taken into account these contradictions, registered the gene in q11 assuming a MOS-like sequence in q22. The HUGEN catalogue describes this sequence as an individual locus MOSL: GEM:08q22/MOSL."

REF

EXP,FAG,EAG "Berdichevsky, Chumakov: Genetika, 24, N2, 366-369, 1988
LOC,CYG,MOL "Caubet &: EMBO J, 4, 2245-2248, 1985
IDN,PRO,FAG "Chumakov &: Gene, 17, 19-26, 1982
LOC,CYG,MOL "Morris CM &: Hum Genet, 81, 339-342, 1989
COM,LOC "Neel BG &: PNAS, 79, (Dec), 7842-7846, 1982
COM,LOC "Pettenati MJ &: Cancer Genet Cytogenet, 37, 221-227, 1989
IDN,LOC,CYG "Prakash K &: PNAS, 79, (Sep), 5210-5214, 1982
COM,LOC "Rosendorff &: Cancer Genet Cytogenet, 24, 137-141, 1987
LOC,CYG,MOL "Testa JR &: Genomics, 3, N1, 44-47, 1988
IDN,SEQ "Watson R &: PNAS, 79, (Jul), 4078-4082, 1982
SEQ,FAG,EVO "Zabarovsky &: Gene, 30, 107-111, 1984
IDN,PRO,FAG "Zabarovsky &: Gene, 23, 379-384, 1983

SWI

SWISSPROT: P00540

KEY

onc

CLA

coding, basic

LOC

08 q11

MIM

MIM: 190060

Смотрите также:

  • протоонкогены: активация путем интеграции ретровирусов
  • MAPK: активация