Gene: [09p13/TPM2] tropomyosin 2 (skeletal muscle beta); [TMSB ]
FUN | The muscle-specific tropomyosin peptides are components of the thin filaments of the sarcomere, the contractile element in muscle, and control contraction in a calcium-dependent manner." |
MOP | The skeletal muscle and cytoskeletal beta tropomyosin isoforms are resulted from the alternative splicing of mRNA encoded by the single gene (MacLeod-1985; Widada-1988)." |
FAG | Two muscle-specific isoforms of tropomyosin, one alpha and one beta, form an alpha-helical dimer, see details in: GEM 15q221/TPM1." |
REF | LOC "Hunt CC &: CCG, 71, 94-95, 1995 PRO,COD,SEQ,EXP,EVO "MacLeod AR &: PNAS, 82, N23, 7835-7839, 1985 PRO,COD,SEQ,EXP,EVO "Widada JS &: NAR, 16, N7, 3109, 1988 |
SWI | SWISSPROT: P07951; TPM2 P06468 |
KEY | myo, cysk |
CLA | coding, basic |
LOC | 09 p13 |
MIM | MIM: 190990 |
SYN | TMSB |
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