Gene: [09p22/IFNB1] interferon, beta 1, fibroblast; [IFF ]
COM | Henry-1984, basing on two cases (translocation and partial monosomy 9p), demonstrated the the localization to 9p21 is the most probable one for IFNB1. Data on the cloning of large genomic fragments from 9p2 also show that IFNB1 and @T:IFNAS, though linked, is located quite far from each other; nevertheless HGM10 indicates for IFNB1 the location 9p22." |
GEN | The gene length is 1 kb. Exons: 1; introns: no. |
EXP | See GEM:07p21/IL6. |
FAG | See GEM:07p21/IL6. |
REF | EXP,GEN "Canaani,
Berg: PNAS, 79, (Sep), 5166-5170, 1982 CLO,SEQ,GEN "Degrave W &: Gene, 14, 137-143, 1981 CLO,SEQ,GEN "Derynck R &: Nature, 285, (19 Jun), 542-546, 1980 EXP,GEN "Fujita &: EMBO J, 7, N11, 3397-3405, 1988 EXP,GEN "Goodbourn, Maniatis: PNAS, 85, N5, 1446-1451, 1988 LOC "Henry L &: Hum Genet, 68, N1, 67-69, 1984 CLO,SEQ,GEN "Houghton M &: NAR, 9, 247-266, 1981 CLO,SEQ,GEN "Houghton M &: NAR, 8, 2885-2894, 1980 EXP,GEN "Keller, Maniatis: PNAS, 85, N10, 3309-3313, 1988 EXP,GEN "Kruys &: Gene, 72, 191-200, 1988 EXP,GEN "Mark DF &: PNAS, 81, N18, 5662-5666, 1984 LOC "Meager A &: Nature, 280, 493-495, 1979 CLO,SEQ,GEN "Ohno, Taniguchi: PNAS, 78, N9, 5305-5309, 1981 LOC "Pitha PM &: Mol Cell Biol, 2, 564-570, 1982a EXP,GEN "Pitha PM &: PNAS, 79, (Jul), 4337-4341, 1982b FAG "Sagar AD &: Somat Cell Mol Genet, 11, 403-408, 1985 FAG "Sagar AD &: Science, 223, 1312-1315, 1984 FAG "Sehgal PB &: PNAS, 83, N14, 5219-5222, 1986 EXP,GEN "Sehgal PB &: PNAS, 79, (Nov), 6932-6936, 1982a FAG "Sehgal PB: BBA, 695, 17-33, 1982b EXP,GEN "Shepard HM &: Nature, 294, (10 Dec), 563-565, 1981 CLO,SEQ,GEN "Taniguchi T &: Gene, 10, 11-15, 1980a CLO,SEQ,GEN "Taniguchi T &: PNAS, 77, N7, 4003-4006, 1980b EXP,GEN "Tavernier J &: Nature, 301, N5901 (17 Feb), 634-636, 1983 CLO,SEQ,GEN "Tavernier J &: NAR, 9, 461-471, 1981 EXP,GEN "Weissenbach J &: PNAS, 77, N12, 7152-7156, 1980 EXP,GEN "Zinn K &: Cell, 34, N3 (1 Oct), 865-879, 1983 LOC "see FAM:IFNA/09p22 and FAM:IFN9/09p22 |
SWI | SWISSPROT: P01574 |
KEY | imm, cyk |
CLA | coding, basic |
LOC | 09 p22 |
MIM | MIM: 147640 |
SYN | IFF |
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