Gene: [09p22/IFNB1] interferon, beta 1, fibroblast; [IFF ]


COM

Henry-1984, basing on two cases (translocation and partial monosomy 9p), demonstrated the the localization to 9p21 is the most probable one for IFNB1. Data on the cloning of large genomic fragments from 9p2 also show that IFNB1 and @T:IFNAS, though linked, is located quite far from each other; nevertheless HGM10 indicates for IFNB1 the location 9p22."

GEN

The gene length is 1 kb. Exons: 1; introns: no.

EXP

See GEM:07p21/IL6.

FAG

See GEM:07p21/IL6.

REF

EXP,GEN "Canaani, Berg: PNAS, 79, (Sep), 5166-5170, 1982
CLO,SEQ,GEN "Degrave W &: Gene, 14, 137-143, 1981
CLO,SEQ,GEN "Derynck R &: Nature, 285, (19 Jun), 542-546, 1980
EXP,GEN "Fujita &: EMBO J, 7, N11, 3397-3405, 1988
EXP,GEN "Goodbourn, Maniatis: PNAS, 85, N5, 1446-1451, 1988
LOC "Henry L &: Hum Genet, 68, N1, 67-69, 1984
CLO,SEQ,GEN "Houghton M &: NAR, 9, 247-266, 1981
CLO,SEQ,GEN "Houghton M &: NAR, 8, 2885-2894, 1980
EXP,GEN "Keller, Maniatis: PNAS, 85, N10, 3309-3313, 1988
EXP,GEN "Kruys &: Gene, 72, 191-200, 1988
EXP,GEN "Mark DF &: PNAS, 81, N18, 5662-5666, 1984
LOC "Meager A &: Nature, 280, 493-495, 1979
CLO,SEQ,GEN "Ohno, Taniguchi: PNAS, 78, N9, 5305-5309, 1981
LOC "Pitha PM &: Mol Cell Biol, 2, 564-570, 1982a
EXP,GEN "Pitha PM &: PNAS, 79, (Jul), 4337-4341, 1982b
FAG "Sagar AD &: Somat Cell Mol Genet, 11, 403-408, 1985
FAG "Sagar AD &: Science, 223, 1312-1315, 1984
FAG "Sehgal PB &: PNAS, 83, N14, 5219-5222, 1986
EXP,GEN "Sehgal PB &: PNAS, 79, (Nov), 6932-6936, 1982a
FAG "Sehgal PB: BBA, 695, 17-33, 1982b
EXP,GEN "Shepard HM &: Nature, 294, (10 Dec), 563-565, 1981
CLO,SEQ,GEN "Taniguchi T &: Gene, 10, 11-15, 1980a
CLO,SEQ,GEN "Taniguchi T &: PNAS, 77, N7, 4003-4006, 1980b
EXP,GEN "Tavernier J &: Nature, 301, N5901 (17 Feb), 634-636, 1983
CLO,SEQ,GEN "Tavernier J &: NAR, 9, 461-471, 1981
EXP,GEN "Weissenbach J &: PNAS, 77, N12, 7152-7156, 1980
EXP,GEN "Zinn K &: Cell, 34, N3 (1 Oct), 865-879, 1983
LOC "see FAM:IFNA/09p22 and FAM:IFN9/09p22

SWI

SWISSPROT: P01574

KEY

imm, cyk

CLA

coding, basic

LOC

09 p22

MIM

MIM: 147640

SYN

IFF

鸯铗痂蝈 蜞赕:

  • Gene: [08^/IFNB3] interferon, beta 3, fibroblast;
  • 门 IFN-徨蜞
  • Gene: [04q/IFNB4] interferon, beta 4, fibroblast;
  • Gene: [02^/IFNB5] interferon, beta 5, fibroblast;
  • 缅睇 眚屦翦痤磬 徨蜞 (IFN1-徨蜞, 仍-徨蜞)