Gene: [09q211/ALDH1] aldehyde dehydrogenase 1, liver cytosolic;


FUN

Systematic name: aldehyde:NAD+ oxidoreductase. Catalyzes reaction: an aldehyde + NAD+ + H(2)O = an acid + NADH."

FAG

Nine aldehyde dehydrogenase isoforms are known: the cytoplasmic, GEM:09q211/ALDH1; the mitochondrial 2, GEM:12q242/ALDH2; the gastric, GEM:17p112/ALDH3; the mitochondrial X, GEM:09p13/ALDH5; GEM:15q26/ALDH6, GEM:11q13/ALDH7, GEM:11q13/ALDH8, GEM:01q2/ALDH9, and GEM:17p112/ALDH10."

REF

CLO,SEQ,EXP "Hsu LC &: Genomics, 5, 857-865, 1989
LOC,MOL,FAG "Hsu LC &: AJHG, 38, 641-648, 1986
CLO,SEQ,EXP "Hsu LC &: PNAS, 82, 3771-3775, 1985
LOC,MOL,FAG "Raghunathan L &: Genomics, 2, 267-269, 1988
CLO,SEQ,EXP "Yoshida A &: Adv Exp Med Biol, 328, 37-44, 1993

SWI

SWISSPROT: P00352

KEY

neu, xen

CLA

coding, basic

LOC

09 q21.1

MIM

MIM: 100640

EZN

ENZYME: 1.2.1.3

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