Gene: [09q22/CTSL] cathepsin L (major excreted protein, MEP);
FUN | [1] Takes
part in lysosomal proteolysis. Belongs to thiol proteases. [2] Systematic name: not known. Catalyzes hydrolysis of proteins. As compared to cathepsin B, cathepsin L exhibits higher activity towards protein substrates, but has little activity on Z-Arg-Arg- NHMeC, and no peptidyl-dipeptidase activity." |
FAG | See GEM:08p22/CTSB. |
REF | LOC,CYG,MOL,FAG "Fan
&: CCG, 51, (HGM10), 996, 1989 CLO,SEQ,EXP,EVO "Gal S, Gottesman: Biochem J, 253, 303-306, 1988 CLO,EXP "Joseph LJ&: J Clin Invest, 81, 1621-1629, 1988 |
SWI | SWISSPROT: P07711 |
KEY | pep, lys |
CLA | coding, basic |
LOC | 09 q22.1-.2 |
MIM | MIM: 116880 |
EZN | ENZYME: 3.4.22.15 |
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