Gene: [15q2/CTSH] cathepsin H;


COM

The HGM Catalogue erroneously indicates EC:3.4.22.6.

FAG

Cathepsin H is assigned to the group of thiol proteinases. Along with other cathepsins (see GEM:08p22/CTSB), it shares homology with plant proteins, such as papain and actinidin."

FUN

Cathepsin H does not have systematic name yet. It catalyzes protein hydrolysis, splitting both internal and N-terminal peptide bonds, i.e. it should be classified as endoaminopeptidase."

REL

GEM:08p22/CTSB; GEM:11p155/CTSD; GEM:01q31/CTSE; GEM:14q112/CTSG; GEM:15q2/CTSH; GEM:09q22/CTSL; GEM:10^/CTSLL."

REF

PRO,SEQ,PEP,EVO "Chan SJ &: PNAS, 83, N20, 7721-7725, 1986
LOC,CYG,MOL,FAG "Wang &: CCG, 46, (HGM9), 710-711, 1987

SWI

 SWISSPROT: P09668

KEY

pep, lys

CLA

coding, basic

LOC

15 q24-25

MIM

 MIM: 116820

EZN

 ENZYME: 3.4.22.16