Gene: [09q32/ORM2] orosomucoid 2 (alpha-1-acid glycoprotein 2); [AGP2 ]
COM | On the controversial data on the regional localization of ORM locus, see GEM:09q32/ORM1 and GEM:09q341/AK1." |
GEN | The gene length is 3.5
kb. Exons: 6; introns: 5. The UPS vicinity contains one Alu-repeat. EX1=
129 bp: 5'-UTL 15 bp, initiator ATG=methionine + 114 bp (38 amino acids),
INT1= 416 bp; EX2= 143 bp (48 amino acids), INT2= 219 bp; EX3= 71 bp
(23 amino acids), INT3= 705 bp; EX4= 108 bp (36 amino acids), INT4= 151 bp; EX5=104 bp (35 amino acids), INT5=1141 bp; EX6= 168 bp: (21 amino acids), terminator TAG, 3'-UTL= 105 bp." |
MOP | The protein contains 201 amino acid residues, MM 40 kD, 45% of the molecular mass is accounted for carbohydrate residues." |
ASS | The serum level of the protein is increased in acute inflammation, i.e. the protein may be assigned to the class of acute-phase reactants." |
MAP | Loci:
GEM:09q32/ORM1; GEM:09q341/AK1; GEM:09q34/ABO. [1] See GEM:09q32/ORM1." |
REF | CLO,SEQ,EXP "Board PG
&: Gene, 44, 127-131, 1986 GEN,STR "Dente L &: EMBO J, 6, 2289-2296, 1987 CLO,SEQ,EXP "Merritt CM, Board PG: Gene, 66, 97-106, 1988 LOC,FAG "Webb GC &: CCG, 47, 18-21, 1988 LOC,FAG "see also GEM:09q32/ORM1 |
SWI | SWISSPROT: P19652 |
KEY | hem, serp |
CLA | coding, basic |
LOC | 09 q32 |
MIM | MIM: 138610 |
SYN | AGP2 |
