Gene: [0Xp221/SMS] spermine synthase;
COM | The spermine synthase gene was found to be located 38 kb telomeric to PEX (GEM:0Xp22/PHEX)." |
FUN | Spermine synthase is 1 of 4 enzymes involved in the synthesis of polyamines from arginine and methionine." |
GEN | The gene length: 54 kb (or over); exons: 11 (Grief-1997). The open reading frame encodes a 368-amino acid protein with little sequence similarity to proteins from bacterial and mammalian sources catalyzing almost identical reactions (Korhonen-1995)." |
FAG | Four enzymes are involved in the synthesis of polyamines from arginine and methionine: spermine synthase, ornithine decarboxylase (GEM:02p25/ODC1, EC:4.1.1.17), S-adenosyl-L-methionine decarboxylase (GEM:06q2/AMD, EC 4.1.1.50), and spermidine synthase (GEM:01p/SRM, EC:2.5.1.16)." |
REL | GEM:0Xp221/SAT. |
REF | GEN,SEQ,LOC "Grieff M
&: Genomics, 44, 227-231, 1997 COD,SEQ "Korhonen V-P &: DNA Cell Biol, 14, 841-847, 1995 |
SWI | SWISSPROT: P52788 |
KEY | aac |
CLA | coding, basic |
LOC | 0X p22.1 |
MIM | MIM: 300105 |
EZN | ENZYME: 2.5.1.22 |
