Gene: [10p112/ITGB1] integrin, beta 1 (antigen CD29 includes MDF2, MSK12); fibronectin receptor, beta polypeptide (antigen CD29 includes MDF2, MSK12); very late activation protein-4 receptor, beta-4 subunit (antigen CD29); [FNRB CD29 ]


FAG

[1] An ITGB1/FNRB-like sequence was found in chr 19p (GEM:19p1/ITGB1L).
[2] On the group of genes that are functionally related to fibronectin, see GEM:02q34/FN1."

PRO

Probe pGEM-32 contains a 2.485-kb cDNA fragment cloned at EcoRI site in the plasmid pGEM1. The probe identifies two fragments, 11.4 and 23 kb in length, in the EcoRI hydrolizate of human gDNA (and only one fragment, 9.1 kb, in the murine gDNA)."

HIS

According to Goodfellow-1989, the antigens MDF2 (monoclonal antibodies A-1A5) and MSK12 (monoclonal antibodies AJ2/AJS), which genes were mapped in chr 10 and registered previously as indipendent markers, are actually identical to beta subunit of the fibronectin receptor. Therefore MDF2 and MSK12 was excluded from the catalogue."

REF

CLO,SEQ,EXP "Argraves WS &: J Cell Biol, 105, 1183-1190, 1987
LOC,MOL,MAP "Carson, Simpson: CCG, 51, (HGM10), 974-975, 1989
LOC,MOL,PRO "Goodfellow &: Ann Hum Genet, 53, 15-22, 1989
LIN,MAG "Myers &: CCG, 51, (HGM10), 1050, 1989
LOC,CYG "Peters PM &: J Exp Med, 159, 1441-1454, 1984
LOC,CYG "Rettig WJ &: PNAS, 81, 6437-6441, 1984
LIN,MAG "Wu &: CCG, 51, (HGM10), 1110-1111, 1989
LOC,CYG "Zhang &: Somat Cell Mol Genet, 14, 99-104, 1988

SWI

SWISSPROT: P05556

KEY

mem, recp

CLA

coding, basic

LOC

10 p11.2

MIM

MIM: 135630

SYN

FNRB CD29

鸯铗痂蝈 蜞赕:

  • Gene: [12q1/ITGA5] integrin, alpha 5 (alpha F; antigen CD49E); fibronectin receptor, alpha polypeptide; [VLA5A CD49E ]
  • HUGEN-疱鲥矧铕 翳狃铐尻蜩磬
  • HUGEN-桧蝈沭桧 徨蜞1