Gene: [12q1/ITGA5] integrin, alpha 5 (alpha F; antigen CD49E); fibronectin receptor, alpha polypeptide; [VLA5A CD49E ]
FAG | [1] The
gene for the beta subunit of fibronectin receptor is mapped in the short
arm of chr 10 (GEM:10p112/ITGB1); in chr
19p, a FNRB-like sequence was found (GEM:19p1/ITGB1L). [2] On the gene group that is functionally related with fibronectin, see GEM:02q34/FN1." |
EVO | Homology was revealed between alpha peptides of platelet glycoprotein IIB (GEM:17q2132/ITGB3), fibronectin receptor (GEM:12q1/ITGA5), and vitronectin receptor (GEM:02q3/ITGAV); all the three genes belong to the integrin family." |
REL | FAM:ITG/00.0 |
REF | PRO,SEQ,EXP "Argraves
WS &: J Cell Biol, 105, 1183-1190, 1987 PRO,SEQ,EXP "Argraves WS &: JBC, 261, 12922-12924, 1986 LOC,MOL,PRO "Sosnoski DM &: J Clin Invest, 81, 1993-1998, 1988 |
SWI | SWISSPROT: P08648 |
KEY | mem, recp |
CLA | coding, basic |
LOC | 12 q11-13 |
MIM | MIM: 135620 |
SYN | VLA5A CD49E |
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