Gene: [11p155/TNNI2] troponin I2, skeletal, fast;
|
FUN |
Troponin I is a constituent protein of the troponin complex located on the thin filament of striated (skeletal and cardiac) muscle and provided a calcium-sensitive switch for striated muscle contraction (see details in FAM:TNN/00.0). Troponin I binds actin (FAM:ACT/00.0) and inhibits actomyosin ATPase activity (FAM:MY/00.0) in the absence of calcium." |
|
REL |
GEM:11p155/TNNT3. |
|
REF |
LOC,FAG "Tiso N &: BBRC, 230, 347-350, 1997 SEQ "Zhu L &: BBA, 1217, 338-340, 1994 |
|
KEY |
myo |
|
CLA |
coding, basic |
|
LOC |
11 p15.5 |
|
MIM |
MIM: 191043 |
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