Gene: [11q13/PPP1CA] protein phosphatase 1, catalytic subunit, alpha isoform;


FUN

 Systematic name: phosphoprotein phosphohydrolase (serine/threonine specific). Catalyzes reaction: a phosphoprotein + H(2)O = a protein + orthophosphate. Removes the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC:3.1.3.48)."

REF

 CLO,COD,SEQ,LOC,EVO,MAM "Barker HM &: Genomics, 7, N2, 159-166, 1990
REV,MEB,FUN "Cohen, Cohen: JBC, 264, 21435-21438, 1989

KEY

 pep, onc

CLA

 coding, basic

LOC

 11 q13

MIM

 MIM: 176875

EZN

 ENZYME: 3.1.3.16

Смотрите также:

  • Gene: [04q2/PPP3CA] protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform; calcineurin A alpha;
  • Gene: [16p1/PPP4C] protein phosphatase 4 (formerly X), catalytic subunit;
  • Gene: [12q24/PPP1CC] protein phosphatase 1, catalytic subunit, gamma isoform;
  • Gene: [19q133/PPP5C] protein phosphatase 5, catalytic subunit;
  • HUGEN-фосфатазы серин-треониновые
  • Gene: [00.0/PPM1A] protein phosphatase 1A, magnesium-dependent, alpha isoform;
  • Gene: [00.0/PPP2R1A] protein phosphatase 2, regulatory subunit A (PR 65), alpha isoform;
  • Gene: [00.0/PPP1R1A] protein phosphatase 1, regulatory subunit 1A (inhibitor);