Gene: [11q223/MMP10] matrix metalloproteinase 10; stromelysin 2 (transin 2);
FUN | Stromelysin is an extracellular endopeptidase. It belongs to collagenase-related connective-tissue-degrading metalloproteinases. The stromelysin 2 catalytic activity is similar to that of stromelysin 1 (GEM:11q223/MMP3), but effect on collagen types III, IV, and V is weak. Digests collagen types I, III, IV, V, fibronectin, and proteoglycan." |
FAG | On stromelysins and collagenase-related connective tissue-degrading metalloproteinases, see GEM:11q223/MMP3." |
REF | LOC "Jung JY &: Ann
Genet, 33, 21-23, 1990 CLO,COD,SEQ,FAG "Muller D &: Biochem J, 253, 187-192, 1988 HUM,RAT,EXP,ENG,FUN "Nicholson &: Biochemistry, 28, N12, 5195-5203, 1989 MAP "Pendas AM &: Genomics, 37, 266-269, 1996 CLO,EXP "Sirum KL, Brinckerhoff: Biochemistry, 28, 8691-8698, 1989 |
SWI | SWISSPROT: P09238 |
KEY | exce, pep |
CLA | coding, basic |
LOC | 11 q22.3 |
MIM | MIM: 185260 |
EZN | ENZYME: 3.4.24.22 |
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