Gene: [11q223/MMP10] matrix metalloproteinase 10; stromelysin 2 (transin 2);


FUN

Stromelysin is an extracellular endopeptidase. It belongs to collagenase-related connective-tissue-degrading metalloproteinases. The stromelysin 2 catalytic activity is similar to that of stromelysin 1 (GEM:11q223/MMP3), but effect on collagen types III, IV, and V is weak. Digests collagen types I, III, IV, V, fibronectin, and proteoglycan."

FAG

On stromelysins and collagenase-related connective tissue-degrading metalloproteinases, see GEM:11q223/MMP3."

REF

LOC "Jung JY &: Ann Genet, 33, 21-23, 1990
CLO,COD,SEQ,FAG "Muller D &: Biochem J, 253, 187-192, 1988
HUM,RAT,EXP,ENG,FUN "Nicholson &: Biochemistry, 28, N12, 5195-5203, 1989
MAP "Pendas AM &: Genomics, 37, 266-269, 1996
CLO,EXP "Sirum KL, Brinckerhoff: Biochemistry, 28, 8691-8698, 1989

SWI

SWISSPROT: P09238

KEY

exce, pep

CLA

coding, basic

LOC

11 q22.3

MIM

MIM: 185260

EZN

ENZYME: 3.4.24.22

鸯铗痂蝈 蜞赕:

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  • MMP-10