Gene: [11q22/CASP4] caspase 4, apoptosis-related cysteine protease (TX protease); interleukin 1, beta convertase (Ice/Ced-3) homolog 2;


FUN

Acts as a negative regulator of programmed cell death.

REF

CLO,SEQ "Faucheu C &: EMBO J, 14, 1914-1922, 1995
CLO,SEQ,LOC "Kamens J &: JBC, 270, 15250-15256, 1995
CLO,SEQ "Munday NA &: JBC, 270, 15870-15876, 1995
LOC "Nasir J &: Mammal Genome, 8, N8, 611-613, 1997

SWI

 SWISSPROT: P49662

KEY

pep, imm, ont

CLA

coding, basic

LOC

11 q22.2-.3

MIM

 MIM: 602664

EZN

 ENZYME: 3.4.22.?

Смотрите также:

  • Gene: [11q22/CASP1] caspase 1, apoptosis-related cysteine protease; interleukin 1, beta, convertase;
  • Gene: [07q35/CASP2] caspase 2 (NEDD2 apoptosis regulatory gene); protease ICH-1 (isoforms L and S); neural precursor cell expressed, developmentally down-regulated 2; holoprosencephaly?;
  • Гены ced-3 и ced-4: Роль в апоптозе