Gene: [12q1/SHMT2] serine hydroxymethyltransferase 2 (mitochondrial);


FUN

[1] Systematic name: 5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase.
[2] The catalyzed reaction: 5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine. Cofactor: pyridoxal-phosphate. The enzyme also catalyses the reaction of glycine with acetaldehyde, to form L-threonine."

REF

CLO,SEQ,LOC "Garrow TA &: JBC, 268, 11910-11916, 1993
LOC "Kao &: PNAS, 64, 1284-1291, 1969
LOC "Law ML &: CCG, 25, 179-180, 1979a
LOC "Law ML, Kao: CCG, 24, 102-114, 1979b

SWI

SWISSPROT: P34897

KEY

aac, mito

CLA

coding, basic

LOC

12 q12-14

MIM

MIM: 138450

EZN

ENZYME: 2.1.2.1

鸯铗痂蝈 蜞赕:

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  • 彦痂磴桎痤犟桁弪桦蝠囗耵屦噻-HUGEN