Gene: [17p112/SHMT1] serine hydroxymethyltransferase 1 (soluble);


FUN

Systematic name: 5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase. The catalyzed reaction: 5,10-methylenetetrahydrofolate + glycine + H(2)O = = tetrahydrofolate + L-serine. Cofactor: pyridoxal-phosphate. The enzyme also catalyses the reaction of glycine with acetaldehyde, to form L-threonine."

REL

GEM:12q1/SHMT2.

PSG

GEM:01p3/SHMT1P.

REF

CLO,SEQ,STR,LOC "Garrow TA &: JBC, 268, 11910-11916, 1993

SWI

SWISSPROT: P34896

KEY

aac

CLA

coding, basic

LOC

17 p11.2

MIM

MIM: 182144

EZN

ENZYME: 2.1.2.1

Смотрите также:

  • Серингидроксиметилтрансфераза-HUGEN