Gene: [16q122/MMP2] matrix metalloproteinase 2 (gelatinase A); collagenase IVA (72kD gelatinase, basement membrane);


FAG

Collagenase IVA belongs to the family of metalloproteinases participating in degradation of extracellular matrix protein, predominantly collagen. In addition to collagenases, several types of stromelysin and stromelysin-like proteins are assigned to this family. For more details about this family, see GEM:11q223/MMP3."

REF

LIN,MAP "Chen LZ &: Genomics, 10, 308-312, 1991
LOC,FAG "Collier IE &: Genomics, 9, 429-434, 1991
PRO,LOC "Fan &: CCG, 51, (HGM10), 996, 1989
LOC,COD,SEQ,PEP "Huhtala P &: Genomics, 6, 554-559, 1990a
GEN,SEQ "Huhtala P &: JBC, 265, 11077-11082, 1990b
MEB,FUN "Liotta &: Nature, 284, 67-68, 1980
MEB,FUN "Salo T &: JBC, 260, 8526-8531, 1985
MEB,FUN "Salo T &: JBC, 258, 3058-3063, 1983

SWI

SWISSPROT: P08253

KEY

exce, pep

CLA

coding, basic

LOC

16 q12.2

MIM

MIM: 120360

EZN

ENZYME: 3.4.24.24

鸯铗痂蝈 蜞赕:

  • MMP: 狃桀沐礤 祛痿钽屙彗: MMP: 溴耱痼牿 爨蝠桕襦
  • 棋豚蜩磬玎 (烫P-2, 觐腚嚆屙噻 IV 蜩镟)
  • Gene: [20q1/MMP9] matrix metalloproteinase 9 (gelatinase B); collagenase IVB (92kD gelatinase, neutrophil);
  • MMP-2