Gene: [17p112/SREBF1] sterol regulatory element binding transcription factor 1;
COM | Sterol regulatory element is a decamer 5'-ATCACCCCAC-3'. |
FUN | SREBF1 is a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor (GEM:19p132/LDLR) and 3-hydroxy-3-methylglutaryl-CoA synthase (see GEM:05p1/HMGCS1)." |
REL | GEM:22q13/SREBF2. |
REF | LOC "Hua X &: Genomics, 25, 667-673, 1995 FUN "Wang X &: Cell, 77, N1, 53-62, 1994 CLO,SEQ,STR "Yokoyama C &: Cell, 75, 187-197, 1993 |
SWI | SWISSPROT: P36956 |
KEY | trc |
CLA | coding, basic |
LOC | 17 p11.2 |
MIM | MIM: 184756 |
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