Gene: [17q2132/ITGB3] integrin, beta 3 (antigen CD61); fibrinogen receptor on platelets, beta subunit; coagulation factor I receptor, beta subunit; glycoprotein IIIa (platelet GPIIb/IIIa complex); neonatal alloimmune thrombocytopenia; [GP3A CD61 ]


COM

ITGB3/GP3A monomer serves as a beta subunit in complex with different alpha subunits to form membrane receptors; their common name is 'integrins' or 'cytoadhesins'; see GEM:17q2132/ITGA2B."

REF

COM,PHE,IDN,FOG "Furihata &: J Clin Invest, 80, 1624-1630, 1987
REV,EVO,SEQ "Hynes RO: Cell, 48, N4, 549-554, 1987
MEB,FUN "Koller &: JBC, 264, N21, 12412-12418, 1989
COM,PHE,IDN,FOG "Kunicki &: J Clin Invest, 67, 717-724, 1981
PRO,GEN,SEQ,EVO "Lanza &: JBC, 265, N30, 18098-18103, 1989
LOC,CYG,MOL "Luo &: CCG, 51, (HGM10), 1036, 1989
PRO,SEQ,LOC "Rosa JP &: Blood, 72, N2, 593-600, 1988
COM,PHE,IDN,FOG "Shibata &: Vox Sang, 51, 334-336, 1986
COM,PHE,IDN,FOG "Von dem Borne &: Vox Sang, 39, 113-120, 1980

KEY

hem, imm, clot, recp, mem

CLA

coding, basic

LOC

17 q21.32

MIM

MIM: 173470

SYN

GP3A CD61

鸯铗痂蝈 蜞赕:

  • Gene: [12q1/ITGA5] integrin, alpha 5 (alpha F; antigen CD49E); fibronectin receptor, alpha polypeptide; [VLA5A CD49E ]
  • Gene superfamily: integrins; (ITGA1 ITGA2 ITGA2B ITGA3 ITGA4 ITGA4L ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAW ITGAX ITGB1 ITGB1L ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8)
  • 匀列韧蚊磐 (羿牝铕 疋屦螓忄龛 I)