Рис. 10 pat


             Нуклеотидная (мРНК) и аминокислотная
            последовательности тирозиназы человека

                             tattgagttcttcaaacattgtagcctctt
  tatggtctctgagaaataactaccttaaacccataatctttaatacttcctaaactttc
  ttaataagagaagctctattcctgacactacctctcatttgcaaggtcaaatcatcatt
  agttttgtagtctattaactgggtttgcttaggtcaggcattattattactaaccttat
  tgttaatattctaaccataagaattaaactattaatggtgaatagagtttttcacttta
  acataggcctatcccactggtgggatacgagccaattcgaaagaaaagtcagtcatgtg
  cttttcagaggatgaaagcttaagataaagactaaaagtgtttgatgctggaggtggga
  gtggtattatataggtctcagccaagacatgtgataatcactgtagtagtagctggaaa
  gagaaatctgtgactccaattagccagttcctgcagaccttgtgaggactagaggaaga

  atg ctc ctg gct gtt ttg tac tgc ctg ctg tgg agt ttc cag acc
  met leu leu ala val leu tyr cys leu leu trp ser phe gln thr	15

  tcc gct ggc cat ttc cct aga gcc tgt gtc tcc tct aag aac ctg
  ser ala gly his phe pro arg ala cys val ser ser lys asn leu	30

  atg gag aag gaa tgc tgt cca ccg tgg agc ggg gac agg agt ccc
  met glu lys glu cys cys pro pro trp ser gly asp arg ser pro	45

  tgt ggc cag ctt tca ggc aga ggt tcc tgt cag aat atc ctt ctg
  cys gly gln leu ser gly arg gly ser cys gln asn ile leu leu	60

  tcc aat gca cca ctt ggg cct caa ttt ccc ttc aca ggg gtg gat
  ser asn ala pro leu gly pro gln phe pro phe thr gly val asp	75

  gac cgg gag tcg tgg cct tcc gtc ttt tat aat agg acc tgc cag
  asp arg glu ser trp pro ser val phe tyr asn arg thr cys gln	90

  tgc tct ggc aac ttc atg gga ttc aac tgt gga aac tgc aag ttt
  cys ser gly asn phe met gly phe asn cys gly asn cys lys phe	105

  ggc ttt tgg gga cca aac tgc aca gag aga cga ctc ttg gtg aga
  gly phe trp gly pro asn cys thr glu arg arg leu leu val arg	120

  aga aac atc ttc gat ttg agt gcc cca gag aag gac aaa ttt ttt
  arg asn ile phe asp leu ser ala pro glu lys asp lys phe phe	135

  gcc tac ctc act tta gca aag cat acc atc agc tca gac tat gtc
  ala tyr leu thr leu ala lys his thr ile ser ser asp tyr val	150

  atc ccc ata ggg acc tat ggc caa atg aaa aat gga tca aca ccc
  ile pro ile gly thr tyr gly gln met lys asn gly ser thr pro	165

  atg ttt aac gac atc aat att tat gac ctc ttt gtc tgg atg cat
  met phe asn asp ile asn ile tyr asp leu phe val trp met his	180

  tat tat gtg tca atg gat gca ctg ctt ggg gga tct gaa atc tgg
  tyr tyr val ser met asp ala leu leu gly gly ser glu ile trp	195

  aga gac att gat ttt gcc cat gaa gca cca gct ttt ctg cct tgg
  arg asp ile asp phe ala his glu ala pro ala phe leu pro trp	210

  cat aga ctc ttc ttg ttg cgg tgg gaa caa gaa atc cag aag ctg
  his arg leu phe leu leu arg trp glu gln glu ile gln lys leu	225

  aca gga gat gaa aac ttc act att cca tat tgg gac tgg cgg gat
  thr gly asp glu asn phe thr ile pro tyr trp asp trp arg asp	240

  gca gaa aag tgt gac att tgc aca gat gag tac atg gga ggt cag
  ala glu lys cys asp ile cys thr asp glu tyr met gly gly gln	255

  cac ccc aca aat cct aac tta ctc agc cca gca tca ttc ttc tcc
  his pro thr asn pro asn leu leu ser pro ala ser phe phe ser	270

  tct tgg cag att gtc tgt agc cga ttg gag gag tac aac agc cat
  ser trp gln ile val cys ser arg leu glu glu tyr asn ser his	285

  cag tct tta tgc aat gga acg ccc gag gga cct tta cgg cgt aat
  gln ser leu cys asn gly thr pro glu gly pro leu arg arg asn	300

  cct gga aac cat gac aaa tcc aga acc cca agg ctc ccc tct tca
  pro gly asn his asp lys ser arg thr pro arg leu pro ser ser	315

  gct gat gta gaa ttt tgc ctg agt ttg acc caa tat gaa tct ggt
  ala asp val glu phe cys leu ser leu thr gln tyr glu ser gly	330

  tcc atg gat aaa gct gcc aat ttc agc ttt aga aat aca ctg gaa
  ser met asp lys ala ala asn phe ser phe arg asn thr leu glu	345

  gga ttt gct agt cca ctt act ggg ata gcg gat gcc tct caa agc
  gly phe ala ser pro leu thr gly ile ala asp ala ser gln ser	360

  agc atg cac aat gcc ttg cac atc tat atg aat gga aca atg tcc
  ser met his asn ala leu his ile tyr met asn gly thr met ser	375

  cag gta cag gga tct gcc aac gat cct atc ttc ctt ctt cac cat
  gln val gln gly ser ala asn asp pro ile phe leu leu his his	390

  gca ttt gtt gac agt att ttt gag cag tgg ctc cga agg cac cgt
  ala phe val asp ser ile phe glu gln trp leu arg arg his arg	405

  cct ctt caa gaa gtt tat cca gaa gcc aat gca ccc att gga cat
  pro leu gln glu val tyr pro glu ala asn ala pro ile gly his	420

  aac cgg gaa tcc tac atg gtt cct ttt ata cca ctg tac aga aat
  asn arg glu ser tyr met val pro phe ile pro leu tyr arg asn	435

  ggt gat ttc ttt att tca tcc aaa gat ctg ggc tat gac tat agc
  gly asp phe phe ile ser ser lys asp leu gly tyr asp tyr ser	450

  tat cta caa gat tca gac cca gac tct ttt caa gac tac att aag
  tyr leu gln asp ser asp pro asp ser phe gln asp tyr ile lys	465

  tcc tat ttg gaa caa gcg agt cgg atc tgg tca tgg ctc ctt ggg
  ser tyr leu glu gln ala ser arg ile trp ser trp leu leu gly	480

  gcg gcg atg gta ggg gcc gtc ctc act gcc ctg ctg gca ggg ctt
  ala ala met val gly ala val leu thr ala leu leu ala gly leu	495

  gtg agc ttg ctg tgt cgt cac aag aga aag cag ctt cct gaa gaa
  val ser leu leu cys arg his lys arg lys gln leu pro glu gly	510

  aag cag cca ctc ctc atg gag aaa gag gat tac cac agc ttg tat
  lys gln pro leu leu met glu lys glu asp tyr his ser leu tyr	525

  cag agc cat tta taa aaggcttaggcaatagagtagggccaaaaagcctgacct
  gln ser his leu ter

  cactctaactcaaagtaatgtccaggttcccagagaatatctgctggtatttttctgta
  aagaccatttgcaaaattgtaacctaatacaaagtgtagccttcttccaactcaggtag
  aacacacctgtctttgtcttgctgttttcactcagcccttttaacattttcccctaagc
  ccatatgtctaaggaaaggatgctatttggtaatgaggaactgttatttgtatgtgaat
  taaagtgctcttatttt

Смотрите также:

  • OCA-1 Ген (TYR Ген, ген тирозиназы, кожно-глазной альбинизм)