Рис. 12 pat
Нуклеотидная (мРНК) и аминокислотная последовательности гена OA1 человека. atg acc cag gca ggc cgg cgg ggt cct ggc aca ccc gag ccg cgt met thr gln ala gly arg arg gly pro gly thr pro glu pro arg 15 ccg cga aca cag ccc atg gcc tcc ccg cgc cta ggg acc ttc tgc pro arg thr gln pro met ala ser pro arg leu gly thr phe cys 30 tgc ccc acg cgg gac gca gcc acg cag ctc gtg ctg agc ttc cag cys pro thr arg asp ala ala thr gln leu val leu ser phe gln 45 ccg cgg gcc ttc cac gcg ctc tgc ctg ggc agc ggc ggg ctc cgc phe arg ala phe his ala leu cys leu gly ser gly gly leu arg 60 ttg gcg ctg ggc ctt ctg cag ctg ctg ccc ggc cgc cgg ccc gcg leu ala leu gly leu leu gln leu leu pro gly arg arg pro ala 75 ggc ccc ggg tcc ccc gcg acg tcc ccg ccg gcc tcg gtc cgc atc gly pro gly ser pro ala thr ser pro pro ala ser val arg ile 90 ctg cgc gct gcc gct gcc tgc gac ctt ctc ggc tgc ctg ggt atg leu arg ala ala ala ala cys asp leu leu gly cys leu gly met 105 gtg atc cgg tcc acc gtg tgg tta gga ttc cca aat ttt gtt gac val ile arg ser thr val trp leu gly phe pro asn phe val asp 120 agc gtc tcg gat atg aac cac acg gaa att tgg cct gct gct ttc ser val ser asp met asn his thr glu ile trp pro ala ala phe 135 tgc gtg ggg agt gcg atg tgg atc cag ctg ttg tac agt gcc tgc cys val gly ser ala met trp ile gln leu leu tyr ser ala cys 150 ttc tgg tgg ctg ttt tgc tat gca gtg gat gct tat ctg gtg atc phe trp trp leu phe cys tyr ala val asp ala tyr leu val ile 165 cgg aga tcg gca gga ctg agc acc atc ctg ctg tat cac atc atg arg arg ser ala gly leu ser thr ile leu leu tyr his ile met 180 gcg tgg ggc ctg gcc acc ctg ctc tgt gtg gag gga gcc gcc atg ala trp gly leu ala thr leu leu cys val glu gly ala ala met 195 ctc tac tac cct tcc gtg tcc agg tgt gag cgg ggc ctg gac cac leu tyr tyr pro ser val ser arg cys glu arg gly leu asp his 210 gcc atc ccc cac tat gtc acc atg tac ctg ccc ctg ctg ctg gtt ala ile pro his tyr val thr met tyr leu pro leu leu leu val 225 ctc gtg gcg aac ccc atc ctg ttc caa aag aca gtg act gca gtg leu val ala asn pro ile leu phe gln lys thr val thr ala val 240 gcc tct tta ctt aaa gga aga caa ggc att tac acg gag aac gag ala ser leu leu lys gly arg gln gly ile tyr thr glu asn glu 255 agg agg atg gga gcc gtg atc aag atc cga ttt ttc aaa atc atg arg arg met gly ala val ile lys ile arg phe phe lys ile met 270 ctg gtt tta att att tgt tgg ttg tcg aat atc atc aat gaa agc leu val leu ile ile cys trp leu ser asn ile ile asn glu ser 285 ctt tta ttc tat ctt gag atg caa aca gat atc aat gga ggt tct leu leu phe tyr leu glu met gln thr asp ile asn gly gly ser 300 ttg aaa cct gtc aga act gca gcc aag acc aca tgg ttt att atg leu lys pro val arg thr ala ala lys thr thr trp phe ile met 315 gga atc ctg aat cca gcc cag gga ttt ctc ttg tct ttg gcc ttc gly ile leu asn pro ala gln gly phe leu leu ser leu ala phe 330 tac ggc tgg aca gga tgc agc ctg ggt ttt cag tct ccc agg aag tyr gly trp thr gly cys ser leu gly phe gln ser pro arg lys 345 gag atc cag tgg gaa tca ctg acc acc tcg gct gct gag ggg gct glu ile gln trp glu ser leu thr thr ser ala ala glu gly ala 360 cac cca tcc cca ctg atg ccc cat gaa aac cct gct tcc ggg aag his pro ser pro leu met pro his glu asn pro ala ser gly lys 375 gtg tct caa gtg ggt ggg cag act tct gac gaa gcc ctg agc atg val ser gln val gly gly gln thr ser asp glu ala leu ser met 390 ctg tct gaa ggt tct gat gcc agc aca att gaa att cac act gca leu ser glu gly ser asp ala ser thr ile glu ile his thr ala 405 agt gaa tcc tgc aac aaa aat gag ggt gac cct gct ctc cca acc ser glu ser cys asn lys asn glu gly asp pro ala leu pro thr 420 cat gga gac cta tga aggggatgtgctgggggtccagaccccatattcctcaga his gly asp leu ter ctcaacaattcttgttctttagaactgtgttctcaccttcccaacactgcactgccgaa gtgtagcggcccccaaaccttgctctcatcaccagctagagcttcttcccgaagggcct ttaggataggagaaagggttcatgcacacacgtgtgagaatggaagagccccctccaga ccactctacagctgctctagccttagttgccactaggaagttttctgaggctggctgta aagtaagtgtaaggtccacatccttggggaagtagttaaataaaatagttatgactg
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