Рис. 20a pat


5'- фланкирующая область гена
E1 бета субъединицы дегидрогеназы

-591                                   DR-1
ttct attcagtgga tttgcaggat gaaatctaag tttacctctt tcatctctca

-540    Enhancer                               DR-1                 DS-1                DR-2
tttaaatgtg gaaaaacgaa atcaataaaa atctatatat gcttattaag cattttaagg

-480    DR-2
agggtgtgaa taaggagtga aagctttgag cagtgactac agcagttttt cgaaagtcaa

-420 DR-3                                                               DR-3
aacaataacc aatgccaatc agtagctctc ttcacctctc acacaataat agagacagga

-360                                                                           Enhancer    DR-4
caggataaaa aagggttaca tttaaaaaaa agtatggatg ttaaaccatt ggaaatggca

  DR-4                                                     GR-4
ctgtaaatga caccggaaaa gatcgcctcc aggcactgtg tggaactttg caaactcggg

-240
tcctcacccg aggaccgcac ggccgacctc ggggaggctc caccccagaa actatttcat

-180
tggcgccacc tctagcccac acttcccctc ttccgcatgc gcacaaggag cagaagccga

-120                                 SP-1                                  CAAT box
ccagctcgtc acgtcgcctt ccccgcccct aaatttccag ttccgattgg tctgtttcat

-60      SP-1                       CAAT box                                     SP-1            DS-2
gggaccgccc ctctggcccg accaatgtgg aagcctcctc gggtgctccg ccctccccgc

+1    DS-2                                                                      ***
aggcggcgtg cggctgcata gcctgagaat cccggtggtg agcggggatg gcggttgtag

61
cggcggctgc cggctggcta ctcaggctca gggcggcagg ggctgagggg cactggcgtc

121           DR-5                 DR-5
ggcttcctgg cgcggggctg gcgcggggct ttttgcaccc cgccgcgactg tcgaggatg

181
cggcccagag gcggcaggtg gctcatttta ctttccagcc agatccggag ccccgggagt

241
acggtgagcc ctgggactgc ccactcggtc


Смотрите также:

  • MSUD.Строение гена E1 бета BCKDH комплекса