Рис. 21 pat
Нуклеотидная и аминокислотная
последовательности аминоацилтрансферазы (DBT)
человека
(-61)*atg gct gca gtc cgt
met ala ala val arg 5
atg ctg aga acc tgg agc agg aat gcg ggg aag ctg att tgt gtt
met leu arg thr trp ser arg asn ala gly lys leu ile cys val 20
cgc tat ttt caa aca tgt ggt aat gtt cat gtt ttg aag cca aat
arg tyr phe gln thr cys gly asn val his val leu lys pro asn 35
tat gtg tgt ttc ttt ggt tat cct tca ttc aag tat agt cat cca
tyr val cys phe phe gly tyr pro ser phe lys tyr ser his pro 50
(+1)
cat cac ttc ctg aaa aca act gct gct ctc cgt*gga cag gtt gtt
his his phe leu lys thr thr ala ala leu arg gly gln val val 65
cag ttc aag ctc tca gac att gga gaa ggg att aga gaa gta act
gln phe lys leu ser asp ile gly glu gly ile arg glu val thr 80
gtt aaa gaa tgg tat gta aaa gaa gga gat aca gtg tct cag ttt
val lys glu trp tyr val lys glu gly asp thr val ser gln phe 95
gat agc atc tgt gaa gtt caa agt gat aaa gct tct gtt acc atc
asp ser ile cys glu val gln ser asp lys ala ser val thr ile 110
act agt cgt tat gat gga gtc att aaa aaa ctc tat tat aat cta
thr ser arg tyr asp gly val ile lys lys leu tyr tyr asn leu 125
gac gat att gcc tat gtg ggg aag cca tta gta gac ata gaa acg
asp asp ile ala tyr val gly lys pro leu val asp ile glu thr 140
gaa gct tta aaa gat tca gaa gaa gat gtt gtt gaa act cct gca
glu ala leu lys asp ser glu glu asp val val glu thr pro ala 155
gtg tct cat gat gaa cat aca cac caa gag ata aag ggc cga aaa
val ser his asp glu his thr his gln glu ile lys gly arg lys 170
aca ctg gca act cct gca gtt cgc cgt ctg gca atg gaa aac aat
thr leu ala thr pro ala val arg arg leu ala met glu asn asn 185
att aag ctg agt gaa gtt gtt ggc tca gga aaa gat ggc aga ata
ile lys leu ser glu val val gly ser gly lys asp gly arg ile 200
ctt aaa gaa gat atc ctc aac tat ttg gaa aag cag aca gga gct
leu lys glu asp ile leu asn tyr leu glu lys gln thr gly ala 215
ata ttg cct cct tca ccc aaa gtt gaa att atg cca cct cca cca
ile leu pro pro ser pro lys val glu ile met pro pro pro pro 230
aag cca aaa gac atg act gtt cct ata cta gta tca aaa cct ccg
lys pro lys asp met thr val pro ile leu val ser lys pro pro 245
gta ttc aca ggc aaa gac aaa aca gaa ccc ata aaa ggc ttt caa
val phe thr gly lys asp lys thr glu pro ile lys gly phe gln 260
aaa gca atg gtc aag act atg tct gca gcc ctg aag ata cct cat
lys ala met val lys thr met ser ala ala leu lys ile pro his 275
ttt ggt tat tgt gat gag att gac ctt act gaa ctg gtt aag ctc
phe gly tyr cys asp glu ile asp leu thr glu leu val lys leu 290
cga gaa gaa tta aaa ccc att gca ttt gct cgt gga att aaa ctc
arg glu glu leu lys pro ile ala phe ala arg gly ile lys leu 305
tcc ttt atg cct ttc ttc tta aag gct gct tcc ttg gga tta cta
ser phe met pro phe phe leu lys ala ala ser leu gly leu leu 320
cag ttt cct atc ctt aac gct tct gtg gat gaa aac tgc cag aat
gln phe pro ile leu asn ala ser val asp glu asn cys gln asn 335
ata aca tat aag gct tct cat aac att ggg ata gca atg gat act
ile thr tyr lys ala ser his asn ile gly ile ala met asp thr 350
gag cag ggt ttg att gtc cct aat gtg aaa aat gtt cag atc tgc
glu gln gly leu ile val pro asn val lys asn val gln ile cys 365
tct ata ttt gac atc gcc act gaa ctg aac cgc ctc cag aaa ttg
ser ile phe asp ile ala thr glu leu asn arg leu gln lys leu 380
ggc tct gtg ggt cag ctc agc acc act gat ctt aca gga gga aca
gly ser val gly gln leu ser thr thr asp leu thr gly gly thr 395
ttt act ctt tcc aac att gga tca att ggt ggt acc ttt gcc aaa
phe thr leu ser asn ile gly ser ile gly gly thr phe ala lys 410
cca gtg ata atg cca cct gaa gta gcc att ggg gcc ctt gga tca
pro val ile met pro pro glu val ala ile gly ala leu gly ser 425
att aag gcc att ccc cga ttt aac cag aaa gga gaa gta tat aag
ile lys ala ile pro arg phe asn gln lys gly glu val tyr lys 440
gca cag ata atg aat gtg agc tgg tca gct gat cac aga gtt att
ala gln ile met asn val ser trp ser ala asp his arg val ile 455
gat ggt gct aca atg tca cgc ttc tcc aat ttg tgg aaa tcc tat
asp gly ala thr met ser arg phe ser asn leu trp lys ser tyr 470
tta gaa aac cca gct ttt atg cta cta gat ctg aaa tga agactg
leu glu asn pro ala phe met leu leu asp leu lys ter 483
(+421)
ataagacattcttgaactttttgagcttccaaagagtatgtaaaccctagctgtgccagc
acatgttcatctttacaatttatattgtaaacgatttgtatcgtatgattaaggatctaa
ggcacaatatttgtcactgttctattagactttttactgaaaatgaataatggtgtaatg
gttctcctggggctgtcacattttataggtcagagtgtgacttcttaatatggtgctgat
gtttttgtgtcaatggcttgaaactggcaagattaacaaaattaggccgggcatggtggc
tcacgcctgtaatccagcactttgggaggcccaggtggggcgatcacctgaggttagaag
tttgagaccagcctggccaacatggtgaaacctggcctctacctaaaaaatacaaaattg
accgggtgtggtggtgggtacc
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