Рис. 18 pat
Нуклеотидная и аминокислотная последовательности бета субъединицы
пропионил КоА карбоксилазы (PCCB) человека
agcgccgtacc
cacgctttagcacatgcgtactcaggtgcgccggtaggggacgcgccggcacagcaaaa
atg gcg gcg gca tta cgg gtg gcg gcg gtc ggg gca agg ctc agc
met ala ala ala leu arg val ala ala val gly ala arg leu ser 15
gtt ctg gcg agc ggt ctc cgc gcc gcg gtc cgc agc ctt tgc agc
val leu ala ser gly leu arg ala ala val arg ser leu cys ser 30
cag gcc acc tct gtt aac gaa cgc atc gaa aac aag cgc cgg acc
gln ala thr ser val asn glu arg ile glu asn lys arg arg thr 45
gcg ctg ctg gga ggg ggc caa cgc cgt att gac gcg cac gac aag
ala leu leu gly gly gly gln arg arg ile asp ala his asp lys 60
cga gga aag cta aca gcc agg gag agg atc agt ctc ttg ctg gac
arg gly lys leu thr ala arg glu arg ile ser leu leu leu asp 75
cct ggc agc ttt gtt gag agc gac atg ttt gtg gaa cac aga tgt
pro gly ser phe val glu ser asp met phe val glu his arg cys 90
gca gat ttt gga atg gct gct gac aag aat aag ttt cct gga gac
ala asp phe gly met ala ala asp lys asn lys phe pro gly asp 105
agc gtg gtc act gga cga ggc cga atc aat gga aga ttg gtt tat
ser val val thr gly arg gly arg ile asn gly arg leu val tyr 120
gtc ttc agt cag gat ttt aca gtt ttt gga ggc agt ctg tca gga
val phe ser gln asp phe thr val phe gly gly ser leu ser gly 135
gca cat gcc caa aag atc tgc aaa atc atg gac cag gcc ata acg
ala his ala gln lys ile cys lys ile met asp gln ala ile thr 150
gtg ggg gct cca gtg att ggg ctg aat gac tct ggg gga gca cgg
val gly ala pro val ile gly leu asn asp ser gly gly ala arg 165
atc caa gaa gga gtg gag tct ttg gct ggc tat gca gac atc ttt
ile gln glu gly val glu ser leu ala gly tyr ala asp ile phe 180
ctg agg aat gtt acg gca tcc gga gtc atc cct cag att tct ctg
leu arg asn val thr ala ser gly val ile pro gln ile ser leu 195
atc atg ggc cca tgt gct ggt ggg gcc gtc tac tcc cca gcc cta
ile met gly pro cys ala gly gly ala val tyr ser pro ala leu 210
aca gac ttc acg ttc atg gta aag gac acc tcc tac ctg ttc atc
thr asp phe thr phe met val lys asp thr ser tyr leu phe ile 225
act ggc cct gat gtt gtg aag tct gtc acc aat gag gat gtt acc
thr gly pro asp val val lys ser val thr asn glu asp val thr 240
cag gag gag ctc ggt ggt gcc aag acc cac acc acc atg tca ggt
gln glu glu leu gly gly ala lys thr his thr thr met ser gly 255
gtg gcc cac aga gct ttt gaa aat gat gtt gat gcc ttg tgt aat
val ala his arg ala phe glu asn asp val asp ala leu cys asn 270
ctc cgg gat ttc ttc aac tac ctg ccc ctg agc agt cag gac ccg
leu arg asp phe phe asn tyr leu pro leu ser ser gln asp pro 285
gct tcc gtc cgt gag tgc cac gat ccc agt gac cgt ctg gtt cct
ala ser val arg glu cys his asp pro ser asp arg leu val pro 300
gag ctt gac aca att gtc cct ttg gaa tca acc aaa gcc tac aac
glu leu asp thr ile val pro leu glu ser thr lys ala tyr asn 315
atg gtg gac atc ata cac tct gtt gtt gat gag cgt gaa ttt ttt
met val asp ile ile his ser val val asp glu arg glu phe phe 330
gag atc atg ccc aat tat gcc aag aac atc att gtt ggt ttt gca
glu ile met pro asn tyr ala lys asn ile ile val gly phe ala 345
aga atg aat ggg agg act gtt gga att gtt ggc aac caa cct aag
arg met asn gly arg thr val gly ile val gly asn gln pro lys 360
gtg gcc tca gga tgc ttg gat att aat tca tct gtg aaa ggg gct
val ala ser gly cys leu asp ile asn ser ser val lys gly ala 375
cgt ttt gtc aga ttc tgt gat gca ttc aat att cca ctc atc act
arg phe val arg phe cys asp ala phe asn ile pro leu ile thr 390
ttt gtt gat gtc cct ggc ttt cta cct ggc aca gca cag gaa tac
phe val asp val pro gly phe leu pro gly thr ala gln glu tyr 405
ggg ggc atc atc cgg cat ggt gcc aag ctt ctc tac gca ttt gct
gly gly ile ile arg his gly ala lys leu leu tyr ala phe ala 420
gag gca act gta ccc aaa gtc aca gtc atc acc agg aag gcc tat
glu ala thr val pro lys val thr val ile thr arg lys ala tyr 435
gga ggt gcc tat gat gtc atg agc tct aag cac ctt tgt ggt gat
gly gly ala tyr asp val met ser ser lys his leu cys gly asp 450
acc aac tat gcc tgg ccc acc gca gag att gca gtc atg gga gca
thr asn tyr ala trp pro thr ala glu ile ala val met gly ala 465
aag ggc gct gtg gag atc atc ttc aaa ggg cat gag aat gtg gaa
lys gly ala val glu ile ile phe lys gly his glu asn val glu 480
gct gct cag gca gag tac atc gag aag ttt gcc aac cct ttc cct
ala ala gln ala glu tyr ile glu lys phe ala asn pro phe pro 495
gca gca gtg cga ggg ttt gtg gat gac atc atc caa cct tct tcc
ala ala val arg gly phe val asp asp ile ile gln pro ser ser 510
aca cgt gcc cga atc tgc tgt gac ctg gat gtc ttg gcc agc aag
thr arg ala arg ile cys cys asp leu asp val leu ala ser lys 525
aag gta caa cgt cct tgg aga aaa cat gca aat att cca ttg taa
lys val gln arg pro trp arg lys his ala asn ile pro leu ter 540
acaaatcaaaggaaaagaaaccaagaactgaattactgtctgcccattcacatcccattc
ctgccttttgcaatcatgatacctggcaatccaaataggttggataagcttataataact
gagttt.attaaa.ttctaga
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