Рис. Ada seq.
Нуклеотидная и аминокислотная последовательности
гена аденозиндеаминазы (adenosine deaminase (AD)
человека.
ATG GCC CAG ACG CCC GCC TTC GAC AAG CCC AAA GTA GAA CTG CAT
met ala gln thr pro ala phe asp lys pro lys val glu leu his 15
GTC CAC CTA GAC GGA TCC ATC AAG CCT GAA ACC ATC TTA TAC TAT
val his leu asp gly ser ile lys pro glu thr ile leu tyr tyr 30
GGC AGG AGG AGA GGG ATC GCC CTC CCA GCT AAC ACA GCA GAG GGG
gly arg arg arg gly ile ala leu pro ala asn thr ala glu gly 45
CTG CTG AAC GTC ATT GGC ATG GAC AAG CCG CTC ACC CTT CCA GAC
leu leu asn val ile gly met asp lys pro leu thr leu pro asp 60
TTC CTG GCC AAA TTT GAC TAC TAC ATG CCT GCT ATC GCG GGC TGC
phe leu ala lys phe asp tyr tyr met pro ala ile ala gly cys 75
CGG GAG GCT ATC AAA AGG ATC GCC TAT GAG TTT GTA GAG ATG AAG
arg glu ala ile lys arg ile ala tyr glu phe val glu met lys 90
GCC AAA GAG GGC GTG GTG TAT GTG GAG GTG CGG TAC AGT CCG CAC
ala lys glu gly val val tyr val glu val arg tyr ser pro his 105
CTG CTG GCC AAC TCC AAA GTG GAG CCA ATC CCC TGG AAC CAG GCT
leu leu ala asn ser lys val glu pro ile pro trp asn gln ala 120
GAA GGG GAC CTC ACC CCA GAC GAG GTG GTG GCC CTA GTG GGC CAG
glu gly asp leu thr pro asp glu val val ala leu val gly gln 135
GGC CTG CAG GAG GGG GAG CGA GAC TTC GGG GTC AAG GCC CGG TCC
gly leu gln glu gly glu arg asp phe gly val lys ala arg ser 150
ATC CTG TGC TGC ATG CGC CAC CAG CCC AAC TGG TCC CCC AAG GTG
ile leu cys cys met arg his gln pro asn trp ser pro lys val 165
GTG GAG CTG TGT AAG AAC TAC CAG CAG CAG ACC GTG GTA GCC ATT
val glu leu cys lys asn tyr gln gln gln thr val val ala ile 180
GAC CTG GCT GGA GAT GAG ACC ATC CCA GGA AGC AGC CTC TTG CCT
asp leu ala gly asp glu thr ile pro gly ser ser leu leu pro 195
GGA CAT GTC CAG GCC TAC CAG GAG GCT GTG AAG AGC GGC ATT CAC
gly his val gln ala tyr gln glu ala val lys ser gly ile his 210
CGT ACT GTC CAC GCC GGG GAG GTG GGC TCG GCC GAA GTA GTA AAA
arg thr val his ala gly glu val gly ser ala glu val val lys 225
GAG GCT GTG GAC ATA CTC AAG ACA GAG CGG CTG GGA CAC GGC TAC
glu ala val asp ile leu lys thr glu arg leu gly his gly tyr 240
CAC ACC CTG GAA GAC CAG GCC CTT TAT AAC AGG CTG CGG CAG GAA
his thr leu glu asp gln ala leu tyr asn arg leu arg gln glu 255
AAC ATG CAC TTC GAG ATC TGC CCC TGG TCC AGC TAC CTC ACT GGT
asn met his phe glu ile cys pro trp ser ser tyr leu thr gly 270
GCC TGG AAG CCG GAC ACG GAG CAT GCA GTC ATT CGG CTC AAA AAT
ala trp lys pro asp thr glu his ala val ile arg leu lys asn 285
GAC CAG GCT AAC TAC TCG CTC AAC ACA GAT GAC CCG CTC ATC TTC
asp gln ala asn tyr ser leu asn thr asp asp pro leu ile phe 300
AAG TCC ACC CTG GAC ACT GAT TAC CAG ATG ACC AAA CGG GAC ATG
lys ser thr leu asp thr asp tyr gln met thr lys arg asp met 315
GGC TTT ACT GAA GAG GAG TTT AAA AGG CTG AAC ATC AAT GCG GCC
gly phe thr glu glu glu phe lys arg leu asn ile asn ala ala 330
AAA TCT AGT TTC CTC CCA GAA GAT GAA AAG AGG GAG CTT CTC GAC
lys ser ser phe leu pro glu asp glu lys arg glu leu leu asp 345
CTG CTC TAT AAA GCC TAT GGG ATG CCA CCT TCA GCC TCT GCA GGG
leu leu tyr lys ala tyr gly met pro pro ser ala ser ala gly 360
CAG AAC CTC TGA
gln asn leu ter
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