Gene: [01q42/ARF1] ADP-ribosylation factor 1;


COM

The ARF1 gene was assigned to Chr 1q42 by fluorescence in situ hybridizatio (Hirai-1996)."

FUN

ARFs are essential and ubiquitous in eukaryotes, being involved in vesicular transport and functioning as activators of phospholipase D (GEM:03q2/PLD1). See details in FAM:ARF/00.0."

GEN

The gene length: 16 kb (approximately); exons: 4 (Lee-1992). Exon 1 (46 bp) contains only untranslated sequence."

FAG

The following genes coding for ADP-ribosylation factors have been found: GEM:03p21/ARF2; GEM:12q13/ARF3; GEM:00.0/ARF4; GEM:17q/ARF4L; GEM:00.0/ARF4P; GEM:00.0/ARF5; GEM:00.0/ARF6. See also GEM:00.0/ARD1 and GEM:00.0/ARL1."

REL

GEM:00.0/ARNO.

REF

MOP,PEP,PRT "Amor JC &: Nature, 372, 704-708, 1994
CLO,SEQ,EXP "Bobak DA &: PNAS, 86, 6101-6105, 1989
LOC,FAG "Hirai M &: Genomics, 34, 263-265, 1996
CLO,SEQ,GEN "Lee C-M &: JBC, 267, 9028-9034, 1992
CLO,SEQ "Mossessova E &: Cell, 92, 415-423, 1998
CLO,SEQ,EXP "Peng ZG &: BioFactors, 2, 45-49, 1989

SWI

SWISSPROT: P32889

KEY

nucm

CLA

coding, basic

LOC

01 q42

MIM

MIM: 103180

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