Gene: [02p21/LSL] leptin, serum levels of; obesity, predisposition to?;
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SUM |
Comuzzie-1997 performed a genome-wide scan and conducted multipoint linkage analysis using a general pedigree-based variance component approach to identify genes with measurable effects on quantitative variation in leptin levels in Mexican Americans. Strong evidence of linkage between serum leptin levels and a microsatellite polymorphism on Chr 2 (D2S1788) was found. On leptin see GEM:07q313/LEP." |
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REF |
LOC,LIN,FOG,EXP "Comuzzie AG &: Nature Genet, 15, N3, 273-276, 1997 ASS,PAT "Considine RV &: New Engl J Med, 334, N5, 292-295, 1996 ASS,PAT "Maffei M &: Nature Med, 1, N11, 1155-1161, 1995 |
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KEY |
serp, lip, mtbd |
|
CLA |
coding, basic |
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LOC |
02 p21 |
|
MIM |
MIM: 601694 |
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