Gene: [02p21/LSL] leptin, serum levels of; obesity, predisposition to?;


SUM

Comuzzie-1997 performed a genome-wide scan and conducted multipoint linkage analysis using a general pedigree-based variance component approach to identify genes with measurable effects on quantitative variation in leptin levels in Mexican Americans. Strong evidence of linkage between serum leptin levels and a microsatellite polymorphism on Chr 2 (D2S1788) was found. On leptin see GEM:07q313/LEP."

REF

LOC,LIN,FOG,EXP "Comuzzie AG &: Nature Genet, 15, N3, 273-276, 1997
ASS,PAT "Considine RV &: New Engl J Med, 334, N5, 292-295, 1996
ASS,PAT "Maffei M &: Nature Med, 1, N11, 1155-1161, 1995

KEY

serp, lip, mtbd

CLA

coding, basic

LOC

02 p21

MIM

MIM: 601694

鸯铗痂蝈 蜞赕:

  • 缅 铈桊屙 (obese gene, ob, LEP)