Gene: [07q313/LEP] leptin (murine obesity homolog); obesity (murine homolog, leptin); [OBS ]


COM

Leptin (from the Greek for 'thin') was the name proposed by Halaas-1995 for the fat-regulating hormone."

REL

GEM:01p31/LEPR (receptor); GEM:02p21/LSL (regulator? of expression)

REF

CLO,SEQ,GEN "Chehab FF &: Nature Genet, 12, N3, 318-320, 1996
CLO,SEQ "Friedman JM &: Genomics, 11, 1054-1062, 1991
LOC "Geffroy S &: Genomics, 28, 603-604, 1995
CLO,SEQ,LOC "Green ED &: Genome Res, 5, N1, 5-12, 1995
CLO,SEQ "Halaas JL &: Science, 269, N5223, 543-546, 1995
CLO,SEQ,STR,LOC "Isse N &: JBC, 270, 27728-27733, 1995
CLO,SEQ,STR,EVO "Masuzaki H &: Diabetes, 44, 855-858, 1995
CLO,SEQ,GEN "Miller SG &: PNAS, 93, N11, 5507-5511, 1996
CLO,SEQ "Zhang Y &: Nature, 372, 425-432, 1994

SWI

SWISSPROT: P41159

KEY

serp, lip, mtbd

CLA

coding, basic

LOC

07 q31.3

MIM

MIM: 164160

SYN

OBS

鸯铗痂蝈 蜞赕:

  • 隋矧桧
  • 缅 铈桊屙 (obese gene, ob, LEP)
  • OB 铃腙
  • Gene: [19q131/CEBPA] CCAAT/enhancer binding protein (C/EBP), alpha; [CEBP ]