Gene: [02q3/GPC1] glypican 1;
FAG | [1]
Glypicans are a family of glycosylphosphatidylinositol (GPI)-anchored cell
surface heparan sulfate proteoglycans. The glypican family is characterized
by a similar core protein size and almost complete conservation of cysteine
residues. In human, the GPC gene family includes following genes: GEM:02q3/GPC1; GEM:00.0/GPC2; GEM:0Xq26/GPC3, GEM:00.0/GPC4, GEM:13q32/GPC5. [2] The glypicans are 1 of the 2 major families of cell-surface proteoglycans, the other being the syndecans, see on them in GEM:02p/SDC1." |
REL | GEM:11p13/CD44 (proteoglycan CD44). |
REF | CLO,SEQ "David G &: J Cell Biol, 111, 3165-3176, 1990 CLO,LOC "Vermeesch JR &: Genomics, 25, 327-329, 1995 REV,FAG,EAG "Weksberg R &: Nature Genet, 12, 225-227, 1996 |
SWI | SWISSPROT: P35052 |
KEY | mem, ont, neu |
CLA | coding, basic |
LOC | 02 q35-37 |
MIM | MIM: 600395 |
