Gene: [11p13/CD44] antigen CD44 (gp90; lymphocyte homing/adhesion receptor; lethal antigen 3); antigen MDU2 (MDU3; monoclonal antibodies A1G3, A3D8); antigen MIC4 (monoclonal antibodies F10.44.2, mab4); Lutheran blood group inhibitor? (MIM:111150; INLU; antigen CD44); [MFI1 S3 MIC4 ]

COM	Antigens MIC4 and MDU3 are described in the MIM Catalogue under the numbers 143040 and 158060?. They were determined to be identical to the product of gene CD44."
FUN	The CD44 peptide possibly inhibits the expression of the Lutheran blood group antigen on the surface of red blood cells."
EXP	Hematopoietic and epithelial forms of antigene CD44 are produced by alternative splicing."
REF	FUN,LOC,CYG,LIN "Ala-Kapee &: CCG, 51, (HGM10), 948-949, 1989 LOC,CYG "Forsberg UH &: Eur J Immunol, 19, 409-412, 1989a LOC,CYG "Forsberg UH &: Immunogenetics, 29, 405-407, 1989b LOC,CYG "Francke U &: Somat Cell Genet, 9, 333-334, 1983 LOC,LIN,MOL,MAP "Glaser &: CCG, 46, (HGM9), 620-621, 1987 LOC,CYG "Goodfellow &: Eur J Immunol, 8, 659-663, 1982 MOU,CLO,COD "Lasky &: Cell, 56, 1045-1055, 1989 PEP,MEB "Omary &: Immunogenetics, 27, 460-464, 1988 IDN,FUN,MEB "Stefanova &: Immunogenetics, 29, 402-404, 1989 LOC,CYG "Van Heyningen &: CCG, 40, (HGM8), 768, 1985
KEY	mem, hem, imm
CLA	coding, basic
LOC	11 p13
MIM	MIM: 107269
SYN	MFI1 S3 MIC4

Смотрите также:

Gene: [11q1/MDU1] antigen MDU1, heavy subunit (p40, monoclonal antibodies 4F2, 44D7); sodium-calcium exchanger (NACAE); [M4F2 MGP4F2 ]

Gene: [17p133/C1QBP] complement component 1, q subcomponent binding protein; hyaluronan-binding protein 1; splicing factor, arginine/serine-rich 1 associated protein (p32); [HABP1 GC1Q-R ]

Gene: [19q132/LU] Lutheran blood group; B-cell adhesion molecule (BCAM); Auberger B antigen; antigen MSK19 (gp95; monoclonal antibody F8); [BCAM MSK19 ]

Gene: [02q3/GPC1] glypican 1;

Gene: [04q2/SPP1] secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); [OPN BNSP ]