Gene: [02q3/ITGAV] integrin, alpha V (antigen CD51); vitronectin receptor, alpha polypeptide; [CD51 VNRA ]


MOP

Vitronectin receptor belongs to the integrins (see FAM:ITG/00.0) and consists of 2 major subunits: a 150kD alpha subunit and a 115-kD beta subunit. Alpha V associates with either the beta 1, beta 3, beta 5 or beta 6. Alpha subunit is composed of an heavy and light chains."

FAG

Vitronectin is mapped to Chr 17q11 (see GEM:17q11/VTN).

REF

CLO,SEQ,EXP,EVO "Cheresh DA &: Cell, 57, 59-69, 1989
LOC "Fernandez-Ruiz E &: CCG, 62, 26-28, 1993
CLO,SEQ,EXP,EVO "Fitzgerald LA &: Biochemistry, 26, 8158-8165, 1987
FUN,MOP "Polack &: Blood, 73, N6, 1519-1524, 1989
LOC,FAG "Sosnoski DM &: J Clin Invest, 81, 1993-1998, 1988
LOC,FAG "Spurr NK, Rooke L: Ann Hum Genet, 55, 217-223, 1991
CLO,SEQ,EXP,EVO "Suzuki S &: JBC, 262, 14080-14085, 1987
CLO,SEQ,EXP,EVO "Suzuki S &: PNAS, 83, N22, 8614-8618, 1986

SWI

SWISSPROT: P06756

KEY

mem, recp

CLA

coding, basic

LOC

02 q31-32

MIM

MIM: 193210

SYN

CD51 VNRA

Смотрите также:

  • Gene: [17q2132/ITGA2B] integrin, alpha 2b (antigen CD41B); coagulation factor I receptor, alpha subunit; fibrinogen receptor on platelets, alpha subunit; glycoprotein IIb (platelet IIb/IIIa complex); thrombasthenia, Glanzmann-Naegeli type (
  • Gene: [16p112/ITGAM] integrin, alpha M (Mac-1a; CD11B; p170); complement component receptor 3, alpha (p170; antigen CD11B); antigen CD11B (macrophage antigen Mac-1-alpha subunit); [CR3A CD11B ]
  • Gene: [12q1/ITGA5] integrin, alpha 5 (alpha F; antigen CD49E); fibronectin receptor, alpha polypeptide; [VLA5A CD49E ]
  • Gene superfamily: integrins; (ITGA1 ITGA2 ITGA2B ITGA3 ITGA4 ITGA4L ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAW ITGAX ITGB1 ITGB1L ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8)