Gene: [05q11/HTR1A] 5-hydroxytryptamine (serotonin) receptor 1A; [ADRBRL1 ]


FAG

[1] The gene for beta-2-adrenergic receptor (HTR-like gene) is assigned to the same chromosome: GEM:05q3/ADRB2.
[2] More than 10 genes for 5-hydroxytryptamine (serotonin) receptor peptides are suggested to exist in human genome: GEM:05q11/HTR1A; GEM:06q1/HTR1B; GEM:01p3/HTR1D; GEM:12^/HTR1DP1; GEM:06q1/HTR1E; GEM:03p1/HTR1F; GEM:13q/HTR2A; GEM:02q3/HTR2B; GEM:0Xq24/HTR2C; GEM:11q23/HTR3; GEM:07q361/HTR5A; GEM:02q1/HTR5B; GEM:01p3/HTR6; GEM:10q2/HTR7."

HIS

In 1987, the HTR1A gene was identified as beta-2-adrenergic receptor-like 1 (Kobilka-1987). Later the gene product identity to serotonin receptor was revealed (Fargin-1988)."

REF

IDN,FUN,EXP "Fargin A &: Nature, 335, 358-360, 1988
LIN,CYG "Gilliam TC &: Genomics, 5, 940-944, 1989
SEQ,GEN,LOC,HIS "Kobilka BK &: Nature, 329, 75-79, 1987
LOC,PRO "Yang-Feng TL &: CCG, 46, (HGM9), 722, 1987

SWI

SWISSPROT: P08908

KEY

neu, recp, sign

CLA

coding, basic

LOC

05 c-q11

MIM

MIM: 109760

SYN

ADRBRL1

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