Gene: [05q13/F2R] coagulation factor II (thrombin) receptor; proteinase activated (protease-activated) receptor 1; [TR CF2R PAR1 ]


FAG

Protease-activated receptors 1 (PAR1; GEM:05q13/F2R), 2 (PAR2; GEM:05q13/F2RL1), 3 (PAR3; GEM:00.0/F2RL2) and 4 (GEM:19p12/PAR4) are members of a unique G protein-coupled receptor family. They are characterized by a tethered peptide ligand at the extracellular amino terminus that is generated by minor proteolysis."

REF

LOC "Bahou WF &: Blood, 82, N5, 1532-1537, 1993
CLO,SEQ "Vu TK &: Cell, 64, N6, 1057-1068, 1991

SWI

SWISSPROT: P25116

KEY

hem, clot, recp

CLA

coding, basic

LOC

05 q13

MIM

MIM: 187930

SYN

TR CF2R PAR1

Смотрите также:

  • PAR рецепторы: активация
  • Тромбин: влияние на активность транскрипционных факторов
  • Коагуляционный фактор F II (Протромбин). Биохимия