Gene: [05q31/IL3] interleukin 3 (colony-stimulating factor, multiple); differentiation factor for basophils (interleukin 3); [MCSF CSFM ]


COM

The GDB indicates the IL3 location less precisely: 05q23-31.

EVO

See GEM:05q31/CSF2.

PRO

Probe IL3 contains a 0.923-kb PstI fragment of gDNA (covering 680 bp of the 5'-untranslated region, 213 bp of exon 1, and 30 bp of intron 1 of the gene IL3) cloned at PstI site in the plasmid pUC8."

REL

See GEM:02q13/IL1A.

REF

GEN,MUT,FAG "Le Beau MM &: PNAS, 90, 5484-5488, 1993
LOC,PRO,PAT "Le Beau MM &: PNAS, 84, N16, 5913-5917, 1987
LOC,PRO,PAT "Le Beau MM &: Cold Spring Harbor Symp, 51, 899-909, 1986
FUN "Valent &: Blood, 73, N7, 1763-1769, 1989
GEN,FAG,MAF "van Leeuwen BH &: Blood, 73, N5, 1142-1148, 1989
GEN,EVO "Yang YC &: Blood, 71, N4, 958-961, 1988
IDN,PRO,SEQ,EXP,EVO "Yang YC &: Cell, 47, 3-10, 1986

SWI

SWISSPROT: P08700

KEY

imm, cyk, onc

CLA

coding, basic

LOC

05 q31

MIM

MIM: 147740

SYN

MCSF CSFM

鸯铗痂蝈 蜞赕:

  • 耐 篦囫蝾 ARE-屐屙螓 (adenylate/uridylate-rich elements)
  • Gene: [00.0/NFIL3] nuclear factor, interleukin 3 regulated (interleukin 3 binding); [IL3BP1 E4BP4 ]
  • Gene: [0Xp223/IL3RAX] interleukin 3 receptor, alpha, X-linked (low affinity; antigen CD123); [IL3RA ]
  • Gene: [0Yp113/IL3RAY] interleukin 3 receptor, alpha, Y-linked (low affinity; antigen CD123); [IL3RA ]
  • 人-3 沐
  • HUGEN-人 3
  • HUGEN-IL3