Gene: [06q2/PLG] plasminogen (fibrinase; fibrinolysin precursor);
EVO | The amino acid sequence of this protein is shown to be highly homologous to that of apolipoprotein(a), the gene for the latter (see GEM:06q27/APOLPA) being closely linked to the PLG gene. APOLPA is involved in the pathogenesis of the atherosclerosis and coronary disease." |
LIK | GEM:02^/PLGL. |
PSG | GEM:00.0/PLGP1; GEM:00.0/PLGP2. |
REF | PEP,SEQ,EVO "Eaton &:
PNAS, 84, N10, 3224-3228, 1987 SEQ,EXP "Forsgren M &: FEBS Lett, 213, 254-260, 1987 LOC,LIN,POL "Murray JC &: AJHG, 40, 338-350, 1987 PRO,LOC "Swisshelm &: CCG, 40, (HGM8), 756, 1985 REV,FUN,EXP,MEB "Wun T-C: CRC Crit Rev Biotech, 8, N2, 131-148, 1988 |
SWI | SWISSPROT: P00747 |
KEY | hem, clot, pep |
CLA | coding, basic |
LOC | 06 q26-27 |
MIM | MIM: 173350 |
EZN | ENZYME: 3.4.21.7 |
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