Gene: [11p155/ADCR] adrenocortical carcinoma; breast cancer chromosome region? (liability); [ADCC ACC BCCR ]
|
COM |
The locus ADCR was excluded from the HGM and GDB catalogues without explaining a reason for it to be done. Probably the authors of these sources supposed that adrenocortical carcinoma and other tumors are related with a complex locus referred to as multiple tumor-associated chromosome region 1 (GEM:11p155/MTACR1)." |
|
HET |
[1] According to Henry-1987/89 (HGM9/10), tumors of many organs may be
related to this locus, including breast cancer (BCCR),
rhabdomyosarcoma (RMSCR; MIM:268210/RMS1), hepatoblastoma, and
nephroblastoma. Therefore loci BCCR and RMSCR indicated in HGM9.5 was
excluded from the following HGM and GEM catalogues.
[2] On rhabdomyosarcoma, see GEM:11p154/MYOD1. [3] Chr 11 contains a number of the loci related with liability to tumors in various organs: GEM:11p155/CDKN1C; GEM:11p155/HRAS; GEM:11p155/MTACR1; GEM:11p154/MYOD1; GEM:11p153/LMO1; GEM:11p13/GUD; GEM:11p13/WT1; GEM:11p1/SPI1; GEM:11p1/ST2; and GEM:11q/ST3." |
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REF |
FAG,LIN,PAT,HET "Ali &: Science, 238, 185-188, 1987 FAG,LIN,PAT,HET "Henry I &: CCG, 51, (HGM10), 1012-1013, 1989a LOC,LIN,MOL "Henry I &: CCG, 51, (HGM10), 1013, 1989b LOC,LIN,MOL "Henry I &: Hum Genet, 81, 273-277, 1989c LOC,LIN,MOL "Henry I &: PNAS, 86, 3247-3251, 1989d LOC,LIN,MOL "Henry I &: Ann Genet, 31, 216-220, 1988 LOC,LIN,MOL "Henry I &: CCG, 46, (HGM9), 629, 1987 FAG,LIN,PAT,HET "Scrable HJ &: Nature, 329, (15 Oct), 645-647, 1987 |
|
KEY |
onc, horm |
|
CLA |
unknown, basic |
|
LOC |
11 p15.5 |
|
MIM |
MIM: 202300 |
|
SYN |
ADCC ACC BCCR |
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