Gene: [11q13/GSTP1] glutathione S-transferase pi (placental; EC:2.5.1.18); fatty acid ethyl ester synthase III, myocardial (EC:3.1.1.67);
|
GEN |
The gene length is 2.9 kb; exons:7; introns: 6 (Morrow-1989; Bora-1997). |
|
FUN |
[1] Glutathione S-transferase participates in metabolism of various
enogenous and exogenous hydrophobic substances. It has a wide substrate
specifity.
[2] Systematic name: RX:glutathione R-transferase. Catalyzes reaction: RX + glutathione = HX + R-S-G." |
|
TIS |
This glutathione transferase isoform is expressed in many organs and tissues, although it is sometimes referred to as a placental form." |
|
HIS |
It was originally assumed that the gene that was mapped to Chr 11 is GST1; however, later it was demonstrated to be GST3." |
|
FAG |
For more details on localization of GST genes and classification of their products, see FAM:GST/00.0." |
|
PSG |
GEM:12q1/GSTPP. |
|
REF |
SEQ,GEN,LOC "Bora PS &: Mol Cell Biochem, 173, 145-151, 1997 CLO,SEQ,STR,LOC "Bora PS &: Genomics, 19, 186-188, 1994a POL "Bora PS &: Hum Mol Genet, 3, 2267, 1994b CLO,SEQ "Bora PS &: JBC, 266, 16774-16777, 1991 EXP,ONT "Hiley &: BBA, 990, 321-324, 1989 CLO,GEN,SEQ,EVO "Morrow CS &: Gene, 75, N1, 3-11, 1989 LOC,CYG,LIN "Silberstein DL, Shows TB: Somat Cell Genet, 8, 667-675, 1982 LOC,MAP "Smith CM &: Genome Res, 7, N8, 835-842, 1997 LOC,CYG,LIN "Suzuki T, Board P: Somat Cell Mol Genet, 10, 319-320, 1984 |
|
KEY |
xen, lip |
|
CLA |
coding, basic |
|
LOC |
11 q13 |
|
MIM |
MIM: 134660 |
|
EZN |
ENZYME: 2.5.1.18 |
Смотрите также:
