Gene: [12p13/CCND2] cyclin D2 (G1/S-specific);


FUN

See GEM:11q133/CCND1.

MOP

All D-type cyclins lack the so-called 'destruction box' identified in the N-terminus of both A-type (GEM:04q/CCNA) and B-type (GEM:05q1/CCNB1) cyclins. See also GEM:11q133/CCND1."

PAT

See GEM:11q133/CCND1. The cyclin D2 gene might be altered in human malignancies. Chromosomal deletions and translocations affecting the short arm of chromosome 12p are among the most common rearrangements observed in childhood acute lymphoblastic leukemia (Raimondi-1986)."

REF

PAT "Raimondi SC &: Blood, 68, 69-75, 1986
FUN,MOP,EXP,EVO,EAG,PAT "see GEM:11q133/CCND1

SWI

SWISSPROT: P30279

KEY

nucm, onc, repr

CLA

coding, basic

LOC

12 p13

MIM

MIM: 123833

鸯铗痂蝈 蜞赕:

  • HUGEN-鲨觌桧
  • HUGEN-鲨觌桧 沭箫稃 D2