Gene: [12p13/CCND2] cyclin D2 (G1/S-specific);
FUN | See GEM:11q133/CCND1. |
MOP | All D-type cyclins lack the so-called 'destruction box' identified in the N-terminus of both A-type (GEM:04q/CCNA) and B-type (GEM:05q1/CCNB1) cyclins. See also GEM:11q133/CCND1." |
PAT | See GEM:11q133/CCND1. The cyclin D2 gene might be altered in human malignancies. Chromosomal deletions and translocations affecting the short arm of chromosome 12p are among the most common rearrangements observed in childhood acute lymphoblastic leukemia (Raimondi-1986)." |
REF | PAT "Raimondi SC &: Blood, 68, 69-75, 1986 FUN,MOP,EXP,EVO,EAG,PAT "see GEM:11q133/CCND1 |
SWI | SWISSPROT: P30279 |
KEY | nucm, onc, repr |
CLA | coding, basic |
LOC | 12 p13 |
MIM | MIM: 123833 |
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