Gene: [17p133/C1QBP] complement component 1, q subcomponent binding protein; hyaluronan-binding protein 1; splicing factor, arginine/serine-rich 1 associated protein (p32); [HABP1 GC1Q-R ]
HIS | Initially the HABP1 was found as a protein (from HeLa cells) that was copurified with the pre-mRNA splicing factor SF2 (GEM:17q2/SFRS1) (Krainer-1991)." |
MOP | The predicted 34-kD protein is highly acidic (estimated pI of 4.04) and contains a hyaluronic acid-binding domain as found in hyaladherin (GEM:11p13/CD44). The protein contains a potential tyrosine sulfation site, 3 predicted N-linked glycosylation sites, and at least 1 potential phosphorylation site for kinases. The recombinant protein, expressed in E. coli, was shown to bind hyaluronic acid-Sepharose (Deb-1996)." |
FAG | Another gene coding for hyaluronan-binding protein has been found: GEM:10q2/HABP2." |
REF | COD,SEQ,MEB,EXP "Deb TB, Datta K: JBC, 271, 2206-2212,
1996 CLO,EXP "Ghebrehiwet B &: J Exp Med, 179, N6, 1809-1821, 1994 LOC "Guo N &: CCG, 77, N3-4, 283-284, 1997 COD,SEQ,EXP "Honore B &: Gene, 134, 283-287, 1993 IDN,EXP "Krainer AR &: Cell, 66, 383-394, 1991 LOC "Majumdar M, Datta K: Genomics, 51, N3, 476-477, 1998 |
SWI | SWISSPROT: Q07021 |
KEY | imm, comp |
CLA | coding, basic |
LOC | 17 p13.3 |
MIM | MIM: 601269 |
SYN | HABP1 GC1Q-R |
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