Gene: [19q134/TNNT1] troponin T1, skeletal, slow; [TNT ]
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FUN |
Troponin T (tropomyosin-binding) is a constituent protein of the troponin complex located on the thin filament of striated (skeletal and cardiac) muscle and provided a calcium-sensitive switch for striated muscle contraction (see details in FAM:TNN/00.0)." |
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FAG |
The contraction of skeletal muscles is regulated by the Ca-dependent protein complex containing tropomyosin dimers (on tropomyosin genes see in: GEM:15q221/TPM1) and 2-3 troponin peptides (on troponin genes see in: FAM:TNN/00.0; on troponin T genes see in: FAM:TNN/00.0)." |
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REF |
EXP,SEQ,MEB,FUN "Gahlmann R &: JBC, 262, 16122-16126, 1987 FUN,MEB "Nadal-Ginard, Mahdavi: J Clin Invest, 84, 1693-1700, 1989 CLO,COD,SEQ,LOC,ASS,EXP "Samson F &: J Neurosci Res, 27, 441-451, 1990 |
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KEY |
myo |
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CLA |
coding, basic |
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LOC |
19 q13.4 |
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MIM |
MIM: 191041 |
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SYN |
TNT |
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