Gene: [04q13/HTN1] histatin 1 (histidine rich salivary protein 1); salivary protein, histatin 1 (histidine rich); [HIS1 SPFHTN1 ]
COM | Sabatini-1989 concluded that the histatin protein family is encoded by at least two closely related loci. vanderSpek-1989 assigned the HTN1 and HTN3 (GEM:04q13/HTN3) genes to Chr 4q13 within 15kb of each other." |
FAG | [1] The main salivary
protein gene cluster is located in Chr 12p (see FAM:SPF12P/12p132), where
there are possibly two genes coding for other histidine-rich salivary
proteins; although in the MIM catalogue a suggestion is made that at least
one of them (see GEM:12p132/SPFGR2) is
related to this or another gene in Chr 4. [2] It is notable that in Chr 4q1 two markers are mapped that is related with a maxillary pathology probably accounted for by disturbances in the turnover of salivary proteins, including statherin (GEM:04q1/DGI; GEM:04q1/JPD; and GEM:04q1/STATH)." |
REF | LOC "Sabatini LM, Azen
EA: BBRC, 160, 495-502, 1989 LOC,MOL,PRO,TIS "vanderSpek JC: AJHG, 45, N3, 381-387, 1989 |
SWI | SWISSPROT: P15515 |
KEY | git, dent |
CLA | coding, basic |
LOC | 04 q13 |
MIM | MIM: 142701 |
SYN | HIS1 SPFHTN1 |
