Gene: [02q1/INHBB] inhibin, beta B; activin, beta B;
FUN | Beta-B inhibin gene encodes one of the chains of inhibins and activins - gonadal glycoprotein hormones - that regulate the secretion of the hypophyseal follicle stimulating hormone (FSH). Beta polypeptide of FSH - follitropin beta - is mapped to Chr 11 (GEM:11p13/FSHB). For more details, see FAM:INH/00.0." |
MOP | [1] Inhibin beta
peptides have MM 10.7 kD (94 amino acids) and have been shown to be
unglycosilated. In SDS electrophoresis, the beta peptide is revealed at the
14-kD band, however this is thought to be a result of abnormal migration in
such a gele. [2] On the alpha peptide structure, see GEM:07p1/INHBA. [3] Structure of inhibin as a whole is described in FAM:INH/00.0." |
FAG | [1] Beta-A inhibin
gene is assigned to Chr 2 (GEM:07p1/INHBA).
Beta-C inhibin gene is mapped to Chr 12 (GEM:12q131/INHBC). [2] See also FAM:INH/00.0." |
REF | LOC,FAG "Barton DE &: Genomics, 5, 91-99, 1989 LOC,FAG,CAG,MOU "Barton DE &: CCG, 46, (HGM9), 578, 1987 COD,SEQ,FAG "Burger HG &: Endocrinology, 122, 1701-1702, 1988 COD,SEQ,FAG "Mason AJ &: BBRC, 135, 957-964, 1986 COD,SEQ,FAG "Mason AJ &: Nature, 318, 659-663, 1985 EXP "Meunier &: PNAS, 85, N1, 247-251, 1988 FUN,PEP,SEQ "Seidah NG &: FEBS Lett, 175, N2, 349-355, 1984 FUN,PEP,SEQ "Sheth &: FEBS Lett, 165, 11-15, 1984 COD,SEQ,FAG "Ulvsback M &: BBRC, 164, N3, 1310-1315, 1989 |
SWI | SWISSPROT: P09529 |
KEY | sex, horm |
CLA | coding, basic |
LOC | 02 c-q13 |
MIM | MIM: 147390 |
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